EDIT

 * a given {@link #getDnaSample() DNA Sample} . The part of the DNA being replicated is defined by the

 * {@link Amplification#getDnaMarker() marker} (also called locus) - implemented in CDM as a {@link DefinedTerm}

 * of term type {@link TermType#DnaMarker}.

 * <BR>

 * To execute the replication {@link Primer primers} (short DNA fractions) are

 * used. They may work in both directions of the DNA part therefore we do have a

 * {@link #getForwardPrimer() forward primer} and a {@link #getReversePrimer() reverse primer}.

 * Most (or all?) amplifications require a {@link #getPurification() purification process}. Additionally

 * some use {@link #getCloning()} for replication.

 * <H3>Quality control</H3>

 * <BR>

 * For quality control the resulting product (PCR) is tested using a chromatographic method called

 * electrophoresis. The parameters (voltage, ladder used, running time, and gel concentration) used

 * for this electrophoresis as well as the resulting

 * We have 2 classes to store the core data for an amplification: {@link Amplification} and {@link AmplificationResult}.

 * <BR>

 * In {@link Amplification} we store all data that is equal for an amplification event which includes amplification

 * of many {@link DnaSample dna samples}. Those data which are relevant only for a specific dna sample are

 * stored in {@link AmplificationResult}. Theoretically this includes data on the resulting PCR. However, as the

 * PCR itself is not persistent we do not store further information on it in the CDM and do not handle

 * <BR>

 * This may change in future: http://dev.e-taxonomy.eu/trac/ticket/3717.

 * <BR>

    @XmlIDREF

    @XmlSchemaType(name = "IDREF")

    @ManyToOne(fetch=FetchType.LAZY)

    private Primer forwardPrimer;

    /** @see #getReversePrimer()*/

    @XmlIDREF

    @XmlSchemaType(name = "IDREF")

    @ManyToOne(fetch=FetchType.LAZY)

    private Primer reversePrimer;

    @XmlIDREF

    @XmlSchemaType(name = "IDREF")

    @ManyToOne(fetch=FetchType.LAZY)

    private MaterialOrMethodEvent purification;

	@XmlElement(name = "Institution")

	@XmlIDREF

	@XmlSchemaType(name = "IDREF")

	@ManyToOne(fetch = FetchType.LAZY)

	@IndexedEmbedded

	@JoinColumn(name="institution_id")

	private Institution institution;

	@Field(analyze = Analyze.NO)

	@NumericField

	private Double gelConcentration;

	//automatically created

	private String labelCache;

	public void setPurification(MaterialOrMethodEvent purification) {

		this.purification = purification;

	}

    /**

     * The institution in which the amplification event took place.

     * Usually the {@link Amplification#getActor()} should be a person

	public void setLadderUsed(String ladderUsed) {

		this.ladderUsed = ladderUsed;

	}

	/**

	 * Returns the labelCache

	 * @return

	/**

	 * This method pushes the {@link Amplification#labelCache label cache} update.

	 */

	public void updateCache(){

        //retrieve data

         //assemble string

         String designation = CdmUtils.concat("_", new String[]{institutionName, staffName, dnaMarkerString, dateString});

         this.labelCache = StringUtils.isBlank(designation) ? "<Amplification:" + getUuid() + ">" : designation ;

	}

	// ********************** CLONE ***********************************/

		try{

			Amplification result = (Amplification)super.clone();

			//purifiaction, ladderUsed, electrophoresisVoltage,

			//gelRunningTime, gelConcentration

			return result;